| Asunto: | Re: [farmacia] informacion sobre Abilify - aripiprazole | | Fecha: | Viernes, 21 de Noviembre, 2003 13:22:21 (-0300) | | Autor: | Leonardo Rodriguez Ribera <rodribera @............ar>
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| En respuesta a: | Mensaje 62 (escrito por Juan) |
Matilde: el producto también se llama Abilitat se usa para el tratamiento de
la esquizofrenia. Dispones de una página en Internet www.abilify.com
ABSTRACT
Atypical antipsychotics generally have a lower propensity for extrapyramidal
side-effects (EPSE), hyperprolactinaemia and tardive dyskinesia than that
associated with typical antipsychotics but may still produce troublesome
side-effects, such as weight gain, cardiac rhythm changes and impaired
glucose tolerance. Aripiprazole is a new atypical antipsychotic with a
unique receptor binding profile that combines partial agonist activity at D2
and 5HT1A receptors with potent antagonism at 5HT2A receptors. Clinical
studies in acute schizophrenic relapse, chronic schizophrenia and acute
mania show it is robustly more effective than placebo. Once-daily
aripiprazole 15-30 mg is as effective as haloperidol 10 mg/day and
risperidone 6 mg/day in short-term treatment of schizophrenia and more
effective than haloperidol 7-10 mg/day in maintenance of response in chronic
schizophrenia. Aripiprazole appears to be well tolerated, with most studies
suggesting a frequency of adverse effects similar to placebo. Aripiprazole
seems not to cause significant EPSE, hyperprolactinaemia, excessive weight
gain or cardiac rhythm disturbance. Limited data suggest that aripiprazole
is not associated with impaired glucose tolerance.
Leonardo
----- Original Message -----
From: "Juan" <goldenwingjcm@hotmail.com>
To: <farmacia@eListas.net>
Sent: Friday, November 21, 2003 12:30 PM
Subject: [farmacia] informacion sobre Abilify - aripiprazole
Agradezco a alguien que posea informacion sobre el aripiprazole, el nombre
comercial es Abilify del Laboratorio Squibb
Gracias
Matilde
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